2000-2006

1:  Pfau PR, Mosley RG, Said A, Gopal DV, Fischer MC, Oberley T, Weiss J, Lee FT Jr, Eckoff D, Reiche M.  Comparison of the effect of non-ionic and ionic contrast agents on pancreatic histology in a canine model. JOP. 2006 Jan 11;7(1):27-33. [PDF]

2:  Cole MP, Chaiswing L, Oberley TD, Edelmann SE, Piascik MT, Lin SM, Kiningham KK, St Clair DK. The protective roles of nitric oxide and superoxide dismutase in adriamycin-induced cardiotoxicity. Cardiovasc Res. 2006 Jan 1;69(1):186-97. [PDF]

3:  Kim A, Oberley LW, Oberley TD. Induction of apoptosis by adenovirus-mediated manganese superoxide dismutase overexpression in SV-40-transformed human fibroblasts. Free Radic Biol Med. 2005 Nov 1;39(9):1128-41. [PDF]

4:  Chaiswing L, Cole MP, Ittarat W, Szweda LI, St Clair DK, Oberley TD. Manganese superoxide dismutase and inducible nitric oxide synthase modify early oxidative events in acute adriamycin-induced mitochondrial toxicity. Mol Cancer Ther. 2005 Jul;4(7):1056-64. [PDF]

5:  Djamali A, Reese S, Oberley T, Hullett D, Becker B. Heat shock protein 27 in chronic allograft nephropathy: a local stress response. Transplantation. 2005 Jun 27;79(12):1645-57. [PDF]

6:  St Clair D, Zhao Y, Chaiswing L, Oberley T. Modulation of skin tumorigenesis by SOD. Biomed Pharmacother. 2005 May;59(4):209-14. Epub 2005 Mar 17. Review. [PDF]

7:  Zhao Y, Chaiswing L, Velez JM, Batinic-Haberle I, Colburn NH, Oberley TD, St Clair DK. p53 translocation to mitochondria precedes its nuclear translocation and targets mitochondrial oxidative defense protein-manganese superoxide dismutase. Cancer Res. 2005 May 1;65(9):3745-50. [PDF]

8:  Djamali A, Reese S, Yracheta J, Oberley T, Hullett D, Becker B. Epithelial-to-mesenchymal transition and oxidative stress in chronic allograft nephropathy. Am J Transplant. 2005 Mar;5(3):500-9.

9:  Kim A, Murphy MP, Oberley TD. Mitochondrial redox state regulates transcription of the nuclear-encoded mitochondrial protein manganese superoxide dismutase: a proposed adaptive response to mitochondrial redox imbalance. Free Radic Biol Med. 2005 Mar 1;38(5):644-54. [PDF]

10:  Zhao Y, Chaiswing L, Oberley TD, Batinic-Haberle I, St Clair W, Epstein CJ, St Clair D. A mechanism-based antioxidant approach for the reduction of skin carcinogenesis. Cancer Res. 2005 Feb 15;65(4):1401-5. [PDF]

11:  Elchuri S, Oberley TD, Qi W, Eisenstein RS, Jackson Roberts L, Van Remmen H, Epstein CJ, Huang TT. CuZnSOD deficiency leads to persistent and widespread oxidative damage and hepatocarcinogenesis later in life. Oncogene. 2005 Jan 13;24(3):367-80. [PDF]

12:  Wheeler DL, Reddig PJ, Ness KJ, Leith CP, Oberley TD, Verma AK. Overexpression of protein kinase C-{epsilon} in the mouse epidermis leads to a spontaneous myeloproliferative-like disease. Am J Pathol. 2005 Jan;166(1):117-26. [PDF]

13:  Torrealba JR, Colburn M, Golner S, Chang Z, Scheunemann T, Fechner JH, Roenneburg D, Hu H, Alam T, Kim HT, Kanmaz T, Oberley T, Knechtle SJ, Hamawy MM. Selenium-binding protein-1 in smooth muscle cells is downregulated in a rhesus monkey model of chronic allograft nephropathy. Am J Transplant. 2005 Jan;5(1):58-67. [PDF]

14:  Li Y, Wheeler DL, Alters W, Chaiswing L, Verma AK, Oberley TD. Early epidermal destruction with subsequent epidermal hyperplasia is a unique feature of the papilloma-independent squamous cell carcinoma phenotype in PKCepsilon overexpressing transgenic mice. Toxicol Pathol. 2005;33(6):684-94. [PDF]

15:  Zhang HJ, Doctrow SR, Xu L, Oberley LW, Beecher B, Morrison J, Oberley TD, Kregel KC. Redox modulation of the liver with chronic antioxidant enzyme mimetic treatment prevents age-related oxidative damage associated with environmental stress. FASEB J. 2004 Oct;18(13):1547-9. [PDF]

16:  Chaiswing L, Cole MP, St Clair DK, Ittarat W, Szweda LI, Oberley TD. Oxidative damage precedes nitrative damage in adriamycin-induced cardiac mitochondrial injury. Toxicol Pathol. 2004 Sep-Oct;32(5):536-47. [PDF]

17:  Fernandez LA, Tsuchida M, Manthei E, Fechner JH Jr, Oberley TD, Leverson GE, Knechtle SJ, Hamawy MM. Immune status assay (ISA): a noninvasive procedure for studying allograft rejection. Transpl Immunol. 2004 Sep-Oct;13(2):147-54. [PDF]

18:  Oberley TD, Xue Y, Zhao Y, Kiningham K, Szweda LI, St  Clair DK. In situ reduction of oxidative damage, increased cell turnover, and delay of mitochondrial injury by overexpression of manganese superoxide dismutase in a multistage skin carcinogenesis model. Antioxid Redox Signal. 2004 Jun;6(3):537-48. [PDF]

19:  Zhong W, Yan T, Webber MM, Oberley TD. Alteration of cellular phenotype and responses to oxidative stress by manganese superoxide dismutase and a superoxide dismutase mimic in RWPE-2 human prostate adenocarcinoma cells. Antioxid Redox Signal. 2004 Jun;6(3):513-22. [PDF]

20:  Ridnour LA, Oberley TD, Oberley LW. Tumor suppressive effects of MnSOD overexpression may involve imbalance in peroxide generation versus peroxide removal. Antioxid Redox Signal. 2004 Jun;6(3):501-12. [PDF]

21:  Kim A, Zhong W, Oberley TD. Reversible modulation of cell cycle kinetics in NIH/3T3 mouse fibroblasts by inducible overexpression of mitochondrial manganese superoxide dismutase. Antioxid Redox Signal. 2004 Jun;6(3):489-500. [PDF]

22:  Oberley TD. Mitochondria, manganese superoxide dismutase, and cancer. Antioxid Redox Signal. 2004 Jun;6(3):483-7. [PDF]

23:  Torrealba JR, Katayama M, Fechner JH Jr, Jankowska-Gan E, Kusaka S, Xu Q, Schultz JM, Oberley TD, Hu H, Hamawy MM, Jonker M, Wubben J, Doxiadis G, Bontrop R, Burlingham WJ, Knechtle SJ. Metastable tolerance to rhesus monkey renal transplants is correlated with allograft TGF-beta 1+CD4+ T regulatory cell infiltrates. J Immunol. 2004 May 1;172(9):5753-64. [PDF]

24:  Kanmaz T, Fechner JJ Jr, Torrealba J, Kim HT, Dong Y, Oberley TD, Schultz JM, Bloom DD, Katayama M, Dar W, Markovits J, Schuler W, Hu H, Hamawy MM, Knechtle SJ.  Monotherapy with the novel human anti-CD154 monoclonal antibody ABI793 in rhesus monkey renal transplantation model. Transplantation. 2004 Mar 27;77(6):914-20. [PDF]

25:  Szweda PA, Camouse M, Lundberg KC, Oberley TD, Szweda LI. Aging, lipofuscin formation, and free radical-mediated inhibition of cellular proteolytic systems. Ageing Res Rev. 2003 Oct;2(4):383-405. Review.

26:  Wheeler DL, Ness KJ, Oberley TD, Verma AK.  Protein kinase Cepsilon is linked to 12-O-tetradecanoylphorbol-13-acetate-induced tumor necrosis factor-alpha ectodomain shedding and the development of metastatic squamous cell carcinoma inprotein kinase Cepsilon transgenic mice. Cancer Res. 2003 Oct 1;63(19):6547-55. [PDF]

27:  Torrealba JR, Fernandez LA, Kanmaz T, Oberley TD, Schultz JM, Brunner KG, Peters D, Fechner JH Jr, Dong Y, Hu H, Hamawy MM, Knechtle SJ.  Immunotoxin-treated rhesus monkeys: a model for renal allograft chronic rejection. Transplantation. 2003 Aug 15;76(3):524-30.

28:  Kahan BW, Jacobson LM, Hullett DA, Ochoada JM, Oberley TD, Lang KM, Odorico JS. Pancreatic precursors and differentiated islet cell types from murine embryonic stem cells: an in vitro model to study islet differentiation. Diabetes. 2003 Aug;52(8):2016-24. [PDF]

29:  Wheeler DL, Ness KJ, Oberley TD, Verma AK.  Inhibition of the development of metastatic squamous cell carcinoma in protein kinase C epsilon transgenic mice by alpha-difluoromethylornithine accompanied by marked hair follicle degeneration and hair loss. Cancer Res. 2003 Jun 15;63(12):3037-42. [PDF]

30:  Li N, Sioutas C, Cho A, Schmitz D, Misra C, Sempf J, Wang M, Oberley T, Froines J, Nel A.  Ultrafine particulate pollutants induce oxidative stress and mitochondrial damage. Environ Health Perspect. 2003 Apr;111(4):455-60. [PDF]

31:  Plymate SR, Haugk KH, Sprenger CC, Nelson PS, Tennant MK, Zhang Y, Oberley LW, Zhong W, Drivdahl R, Oberley TD. Increased manganese superoxide dismutase (SOD-2) is part of the mechanism for prostate tumor suppression by Mac25/insulin-like growth factor binding-protein-related protein-1. Oncogene. 2003 Feb 20;22(7):1024-34. [PDF]

32:  Fernandez LA, Torrealba J, Yagci G, Ishido N, Tsuchida M, Tae Kim H, Dong Y, Oberley T, Fechner J, Colburn MJ, Schultz J, Kanmaz T, Hu H, Knechtle SJ, Hamawy MM. Piceatannol in combination with low doses of cyclosporine A prolongs kidney allograft survival in a stringent rat transplantation model. Transplantation. 2002 Dec 15;74(11):1609-17.

33:  Li N, Wang M, Oberley TD, Sempf JM, Nel AE. Comparison of the pro-oxidative and proinflammatory effects of organic diesel exhaust particle chemicals in bronchial epithelial cells and macrophages. J Immunol. 2002 Oct 15;169(8):4531-41. [PDF]

34:  Lin TM, Ko K, Moore RW, Simanainen U, Oberley TD, Peterson RE.  Effects of aryl hydrocarbon receptor null mutation and in utero and lactational 2,3,7,8-tetrachlorodibenzo-p-dioxin exposure on prostate and seminal vesicle development in C57BL/6 mice.Toxicol Sci. 2002 Aug;68(2):479-87. [PDF]

35:  Elegbede JA, Hayes K, Schell K, Oberley TD, Verma AK. Induction of apoptosis and inhibition of papilloma formation may signal a new role for okadaic acid. Life Sci. 2002 Jun 14;71(4):421-36. [PDF]

36:  Zhao Y, Oberley TD, Chaiswing L, Lin SM, Epstein CJ, Huang TT, St  Clair D. Manganese superoxide dismutase deficiency enhances cell turnover via tumor promoter-induced alterations in AP-1 and p53-mediated pathways in a skin cancer model. Oncogene. 2002 May 30;21(24):3836-46.

37:  Miller FJ Jr, Sharp WJ, Fang X, Oberley LW, Oberley TD, Weintraub NL. Oxidative stress in human abdominal aortic aneurysms: a potential mediator of aneurysmal remodeling. Arterioscler Thromb Vasc Biol. 2002 Apr 1;22(4):560-5. [PDF]

38:  Oberley TD.  Oxidative damage and cancer. Am J Pathol. 2002 Feb;160(2):403-8. [PDF]

39:  Yang J, Lam EW, Hammad HM, Oberley TD, Oberley LW.  Antioxidant enzyme levels in oral squamous cell carcinoma and normal human oral epithelium. J Oral Pathol Med. 2002 Feb;31(2):71-7.

40:  Becker BN, Jacobson LM, Hullett DA, Radke NA, Oberley TD, Brazy PC, Kirk AD. Type 2 angiotensin II receptor expression in human renal allografts: an association with chronic allograft nephropathy. Clin Nephrol. 2002 Jan;57(1):19-26.

41:  Oberley TD. Ultrastructural localization and relative quantification of 4-hydroxynonenal-modified proteins in tissues and cell compartments. Methods Enzymol. 2002;352:373-7.

42:  De Las Casas LE, Hoerl HD, Bardales RH, Pirsch JD, Sempf JM, Wetzel DJ, Stewart J 3rd, Oberley TD, Kurtycz DF. Utility of urinary cytology for diagnosing human polyoma virus infection in transplant recipients: a study of 37 cases with electron microscopic analysis. Diagn Cytopathol. 2001 Dec;25(6):376-81. [PDF]

43:  Raineri I, Carlson EJ, Gacayan R, Carra S, Oberley TD, Huang TT, Epstein CJ. Strain-dependent high-level expression of a transgene for manganese superoxide dismutase is associated with growth retardation and decreased fertility. Free Radic Biol Med. 2001 Oct 15;31(8):1018-30. [PDF]

44:  Zhong W, Oberley TD. Redox-mediated effects of selenium on apoptosis and cell cycle in the LNCaP human prostate cancer cell line. Cancer Res. 2001 Oct 1;61(19):7071-8. [PDF]

45:  Jansen AP, Dreckschmidt NE, Verwiebe EG, Wheeler DL, Oberley TD, Verma AK. Relation of the induction of epidermal ornithine decarboxylase and hyperplasia to the different skin tumor-promotion susceptibilities of protein kinase C alpha, -delta and -epsilon transgenic mice. Int J Cancer. 2001 Sep 1;93(5):635-43.

46:  Cho CS, Burkly LC, Fechner  JH Jr, Kirk AD, Oberley TD, Dong Y, Brunner KG, Peters D, Tenhoor CN, Nadeau K, Yagci G, Ishido N, Schultz JM, Tsuchida M, Hamawy MM, Knechtle SJ.  Successful conversion from conventional immunosuppression to anti-CD154 monoclonal antibody costimulatory molecule blockade in rhesus renal allograft recipients. Transplantation. 2001 Aug 27;72(4):587-97.

47:  Fechner  JH Jr, Dong Y, Hong X, Brunner KG, Tsuchida M, Neville D, Scharff J, Lee F, Oberley TD, Peters D, Schultz JM, Manthei ER, Hamawy MM, Knechtle SJ. Graft survival in a rhesus renal transplant model after immunotoxin-mediated T-cell depletion is enhanced by mycophenolate and steroids. Transplantation. 2001 Aug 27;72(4):581-7.

48:  Zhao Y, Xue Y, Oberley TD, Kiningham KK, Lin SM, Yen HC, Majima H, Hines J, St  Clair D. Overexpression of manganese superoxide dismutase suppresses tumor formation by modulation of activator protein-1 signaling in a multistage skin carcinogenesis model. Cancer Res. 2001 Aug 15;61(16):6082-8. [PDF]

49:  De Las Casas LE, Hoerl HD, Oberley TD, Hafez GR, Sempf JM, Shalkham JE, Kurtycz DF. Myoepithelioma presenting as a midline cystic tongue lesion: cytology, histology, ancillary studies, and differential diagnosis. Diagn Cytopathol. 2001 Jun;24(6):403-7. [PDF]

50:  Oberley TD, Verwiebe E, Zhong W, Kang SW, Rhee SG.  Localization of the thioredoxin system in normal rat kidney. Free Radic Biol Med. 2001 Feb 15;30(4):412-24.

51:  Jansen AP, Verwiebe EG, Dreckschmidt NE, Wheeler DL, Oberley TD, Verma AK. Protein kinase C-epsilon transgenic mice: a unique model for metastatic squamous cell carcinoma. Cancer Res. 2001 Feb 1;61(3):808-12. [PDF]

52:  Kim ND, Oberley TD, Yasukawa-Barnes J, Clifton KH. Stem cell characteristics of transplanted rat mammary clonogens. Exp Cell Res. 2000 Oct 10;260(1):146-59. [PDF]

53:  Chen Z, Oberley TD, Ho Y, Chua CC, Siu B, Hamdy RC, Epstein CJ, Chua BH. Overexpression of CuZnSOD in coronary vascular cells attenuates myocardial ischemia/reperfusion injury. Free Radic Biol Med. 2000 Oct 1;29(7):589-96.

54:  Lagoo AS, Buckley PJ, Burchell LJ, Peters D, Fechner JH, Tsuchida M, Dong Y, Hong X, Brunner KG, Oberley TD, Hamawy MM, Knechtle SJ. Increased glomerular deposits of von Willebrand factor in chronic, but not acute, rejection of primate renal allografts. Transplantation. 2000 Sep 27;70(6):877-86.

55:  Zainal TA, Oberley TD, Allison DB, Szweda LI, Weindruch R. Caloric restriction of rhesus monkeys lowers oxidative damage in skeletal muscle. FASEB J. 2000 Sep;14(12):1825-36. [PDF]

56:  Hall DM, Xu L, Drake VJ, Oberley LW, Oberley TD, Moseley PL, Kregel KC. Aging reduces adaptive capacity and stress protein expression in the liver after heat stress. J Appl Physiol. 2000 Aug;89(2):749-59. [PDF]

57:  Li S, Yan T, Yang JQ, Oberley TD, Oberley LW. The role of cellular glutathione peroxidase redox regulation in the suppression of tumor cell growth by manganese superoxide dismutase. Cancer Res. 2000 Jul 15;60(14):3927-39. [PDF]

58:  Bostwick DG, Alexander EE, Singh R, Shan A, Qian J, Santella RM, Oberley LW, Yan T, Zhong W, Jiang X, Oberley TD. Antioxidant enzyme expression and reactive oxygen species damage in prostatic intraepithelial neoplasia and cancer. Cancer. 2000 Jul 1;89(1):123-34. [PDF]

59:  Oberley TD, Zhong W, Szweda LI, Oberley LW. Localization of antioxidant enzymes and oxidative damage products in normal and malignant prostate epithelium. Prostate. 2000 Jul 1;44(2):144-55. [PDF]

60:  Lam EW, Hammad HM, Zwacka R, Darby CJ, Baumgardner KR, Davidson BL, Oberley TD, Engelhardt JF, Oberley LW.  Immunolocalization and adenoviral vector-mediated manganese superoxide dismutase gene transfer to experimental oral tumors. J Dent Res. 2000 Jun;79(6):1410-7.

61:  Becker BN, Jacobson LM, Becker YT, Radke NA, Heisey DM, Oberley TD, Pirsch JD, Sollinger HW, Brazy PC, Kirk AD. Renin-angiotensin system gene expression in post-transplant hypertension predicts allograft function. Transplantation. 2000 Apr 15;69(7):1485-91.

62:  Kusaka S, Grailer AP, Fechner JH Jr, Jankowska-Gan E, Oberley T, Sollinger HW, Burlingham WJ. Clonotype analysis of human alloreactive T cells: a novel approach to studying peripheral tolerance in a transplant recipient. J Immunol. 2000 Feb 15;164(4):2240-7. [PDF]

63:  Reddig PJ, Dreckschmidt NE, Zou J, Bourguignon SE, Oberley TD, Verma AK. Transgenic mice overexpressing protein kinase C epsilon in their epidermis exhibit reduced papilloma burden but enhanced carcinoma formation after tumor promotion. Cancer Res. 2000 Feb 1;60(3):595-602.

64:  Hall DM, Oberley TD, Moseley PM, Buettner GR, Oberley LW, Weindruch R, Kregel KC. Caloric restriction improves thermotolerance and reduces hyperthermia-induced cellular damage in old rats. FASEB J. 2000 Jan;14(1):78-86.